Best Casino Hotels in St. Louis Missouri 2026 Guide
St. Louis, Missouri, boasts vibrant casino hotels blending luxury stays with non-stop gaming excitement in 2026. From riverside resorts to urban escapes, these properties offer slots, poker rooms, shows, and fine dining. Perfect for weekend getaways or extended vacations.
Explore top-rated options with detailed amenities, room rates, and guest reviews. Whether seeking high-stakes action or family-friendly fun, St. Louis casino hotels deliver unforgettable experiences along the Mississippi.
Hollywood Casino & Hotel St. Louis
Premier destination with 2,800+ slots and 10-table poker room. Luxe rooms feature river views and spa services.
- Nightly rates from $149
- Multiple restaurants including steakhouse
- Live entertainment weekly
River City Casino & Hotel
Intimate vibe with 950 slots, blackjack, and craps. Award-winning hotel emphasizes comfort and convenience.
- Rooms from $129/night
- Indoor pool and fitness center
- Shuttle to downtown attractions
Pinnacle Entertainment Options
Part of Ameristar network, offering expansive gaming floors and upscale accommodations.
- 1,900 slots and video poker
- Buffet with 300+ seats
- Event center for concerts
Emerging 2026 Hotspots
New developments enhancing St. Louis' casino scene with modern twists.
- Eco-friendly suites opening Q1
- VR gaming lounges
- Expanded sports betting areas